Ọkpụkpụ ọbara na-ekpuchi bụ ikike kachasị mkpa nke akụkụ ahụ iji kwụsị ọbara ọgbụgba mgbe mgbidi nke arịa ọbara ji emebi, na nkwụsị ọbara na-ekpochapụ mgbe a na-achọkwaghị ha. Echiche nke ọbara coagulability bụ ihe jikọrọ ya na usoro nke homeostasis, ọrụ ya bụ iji chekwaa ọbara. Homeostasis nwere usoro abụọ:
- Isi - vascular-platelet. Na ya, platelets na-ejikọta ma na-etolite ihe a na-akpọ "thrombus" ọcha, nke platelets na-emekarị.
- Nke abụọ - coagulation (ọ na-- coagulation nke ọbara). Na ya, a na-eji nnukwu eriri nke ebe ahụ mebiri emebi na-eji eriri fibrin kee, nke a na-akpọkwa "eriri ọbara ọbara". E nyere ya aha a n'ihi na eriri fibrin bụ nke erythrocytes.
Ya mere, usoro nke ịmịnye ọbara bụ ihe mgbagwoju anya, ọrụ ya na ahụ dịkwa oke mkpa. Ihe ọ bụla metụtara ọrịa ọbara nwere ike ịpụta ọrịa na iduga ya. Ekwesiri ime ka o doo anya na akpatre ikpeazụ nke homeostasis bụ fibrinolysis, nke ọbara na-agbaji mgbe ụgbọ ahụ na-alọghachi na mkpa ọkpụkpụ ụbụrụ ga-apụ n'anya.
Ndị na-egosi maka ịkọwa ọbara
A na-akpọkwa nyocha ọbara ọbara coaguloramma. Iji nyocha ọbara maka clotting, ịkwesịrị ịchọpụta ihe gosiri na nke a. N'ọtụtụ ọrịa, ọkpụkpụ ọbara nwere ike ịda mbà, ọnụnọ ha bụkwa ihe ndabere maka ikwenye na ike nke clotting:
- ọrịa autoimmune;
- ọrụ imeju dị iche;
- ọrịa pathovascular;
- varicose veins;
- ọrịa shuga ;
- hemochromatosis .
Ọzọkwa, ntule coagulation dị mkpa maka ọnọdụ ụfọdụ:
- ime ime;
- oge nhazi ma ọ bụ oge ọhụụ;
- akara na ọgwụgwọ nke anticoagulants;
- Ọ bụrụ na ịchọọ ịchọrọ ọnwụ ọbara dị ogologo, ọ dị mkpa ka ịlele ọnyá.
Nkọwa nke nyocha ọbara maka clotting
Tupu ị na-ekwu banyere usoro ọbara na-ejikọta analysis, a ghaghị ịkọwapụta na na nyocha ọ bụla ndị a nwere ike ịdịtụ iche, ya mere okwu ikpeazụ bụ maka dọkịta na-aga. Ekwesịrị ịghọta na mkpụrụ akwụkwọ coagulogram dịgasị iche n'oge ime, dabere na trimester.
Ya mere, nyocha ọbara zuru ezu maka clotting nwere ụkpụrụ asatọ, nke na-enye nkọwa nke ọbara na-ejikọta:
- Ọbara ọbara maka oge clotting. Ụkpụrụ nke clotting oge bụ 5-10 nkeji (maka ọbara ọbara, na capillary - 2 nkeji). Nrịbawanye na njedebe na-egosi obere coagulability, na ọnụ na-ekpuchi clotting.
- APTTV bụ oge nke thromboplastin anya. Ụkpụrụ ahụ sitere na 24 ruo 35 sekọnd. Ọganihu na oge na-egosi ike na-ezighị ezi, na mbenata oge maka hypercoagulability.
- The prothrombin index bụ oge prothrombin, nke a na-agụ iji nyochaa ụzọ mpụga nke ụzọ mpụta. Ọnụego ahụ sitere na 80 ruo 120%. Mbelata na njirimara na-egosi hypercoagulable, na mmụba na arụmọrụ ọrụ nke ọbara coagulation.
- Fibrinogen bụ protein na plasma. N'ihe ngosi, ihe ngosi sitere na 5.9 ruo 11.7 μmol / l. Ọ nwere ike ịbawanye na mbufụt, afọ ime, ọkụ na nkụchi obi. Ihe ngosi a nwere ike ikwu banyere ọrịa DIC ma ọ bụ ọrịa imeju.
- Oge Thrombin bụ nyocha nke ikpeazụ nke coagulation. Dị ka ọ dị, ọnụ ọgụgụ a sitere na 11 ruo 17.8 sekọnd. Enweghị ụbụrụ fibrinogen, hyperbilirubinemia, ma ọ bụ ọgwụgwọ na heparin, enwere ike inwe mmụba, na nkwụsị oge - na ụba fibrinogen na ọbara, ma ọ bụ na ọrịa AIDS.
- Oge nkedo plasma recalcification bụ nkịtị - site na 60 ruo 120 sekọnd.
- Mkpụrụ obi na-eme ka akpụkpọ ụkwụ sie ike. Ugbu a, a dịghị eji ule a eme ihe mgbe niile. Ụdị nke si 3 ruo 11 nkeji.
- Ntughari nke ọbara ọbara. Dika nhazi di site na 44 ruo 65%.
Kedu ka e si eme ọbara ahụ na-akpụ akpụ?
A na-emekarị ule ọbara na-eme ka a na-eme ya na vitamin, ma, dịka ọmụmaatụ, na nyocha nke coagulation nke ọbara zuru oke - thromboelastography, a na-atụle ọnọdụ nke Invivo.
Iji mee nnyocha ọbara n'ozuzu maka clotting, awa 8 tupu ule ahụ ekwesighi iri nri. A na-ewepụ ọbara maka nyocha iji nyocha ọbara ọbara. Iji chọpụta ikike nke ịkpụ ọbara ọbara na plalets na-edozi ọbara iji nyochaa ọbara site na mkpịsị aka.