Mkpụrụ hormoni antidiuretic ma ọ bụ hormonone vasopressin bụ peptide. O nwere ihe amino acid itoolu. Ọkara ndụ ya bụ minit 2-4. A na - emepụta hormone a na nnukwu akụkụ sel hypothalamus, site na ebe ahụ a na - ebute ya na neurohypophysis. A na-emegharị na axons n'ihi protein-vectors.
Ọrụ nke hormone vasopressin
Isi ọrụ nke hormone bụ njikwa mmiri metabolism. Ya mere, a na-akpọ ya antidiuretic. Ozugbo ọnụ ọgụgụ ADH na-abawanye n'ahụ, ụda urine tọhapụrụ na-arịwanye elu.
Ma n'eziokwu, ọ na-achọpụta na vasopressin bụ hormone dị iche iche na-arụ ọrụ na ọrụ dị iche iche na-eme nnukwu ego. Otu kachasị n'ime ha bụ:
- mụbara ọbara olu na-ekesa site na arịa;
- eme ka ụda olu ahụ dị ụtọ;
- arụ ọrụ nke mkpụrụ ndụ ọbara nke platelets;
- usoro nhazi usoro nchekwa;
- na-ebelata ego sodium n'ime ọbara;
- a na-egbu egbu nke abụba abụba.
Ụdị nke vasopressin
Ọ bụrụ na ọnụ ọgụgụ nke vasopressin kwekọrọ n'ụkpụrụ na nyocha nke ule, ọ dịghị ihe kpatara nchegbu. Ụkpụrụ njikwa ederede dị ka nke a:
- na osmolality nke plasma 270-280 mosm / kg -
- 280-285 mosm / kg -
- 285-290 mosm / kg - 1-5 pg / mol;
- 290-295 mosm / kg - 2-7 pg / mol;
- 295-300 mosm / kg - 4-12 pg / mol.
Dika usoro nke eme ihe, enwere ike iwere hormones vasopressin na oxytocin dika ndi yiri ya. Ihe kachasị dị iche bụ na nke ikpeazụ ahụ nwere ihe abụọ amino acid fọdụrụ. Ma nke a anaghị egbochi hormone ahụ site n'igosi ọrụ ọzọ gbasara mkpali nke mmiri ara ehi, dịka ọmụmaatụ.
Hypofunction nke hormone vasopressin
Ọ bụrụ na ihe dị n'anụ ahụ ezughị, shuga na-arịa ọrịa shuga pụrụ ịzụlite. Ọrịa a na-eji mmegbu nke ọrụ mmiri nyochaghachi site na real tubules. A na-eme ka ogo ADH dị mfe site n'iji ethanol na glucocorticoids.
Hyperfunction nke antidiuretic hormone vasopressin
ADH nwere ike imepụta ya:
- enwe mmetụta uche na nke anụ ahụ;
- nkwụsị azụ;
- ọgwụ na-ezughị ezu ;
- ọnụ ọgụgụ dị na ọbara a na-ekesa n'akụkụ akwa ahụ;
- nnukwu prophytent porphyria;
- ụbụrụ ụbụrụ;
- oyi baa;
- akpọnwụ mmadụ.
Nsogbu ahụ bụ ọnụ ala na njupụta nke plasma ọbara na ntọhapụ nke mmamịrị nke oke elu.