Iji merie ọrịa ọrịa fungal, a na-emepụta ọtụtụ ọgwụ taa. Na tupu dọkịta ọ bụla enwere ike ịhọrọ ọgwụ kachasị mma na nke a ma ọ bụ nke ahụ.
Ihe mgbochi Ketoconazole ma ọ bụ ihe ndị ọzọ na-adabere na ya bụ ndị ọrụ antifungal dị iche iche. Ha na-enyere aka na-emeso mycoses systemic, ya bụ, ọrịa ndị na-egbu egbu, nakwa nke ọrịa fungal na-adịghị elu - mycoses, seborrhea.
Ketoconazole nwere mmetụta na-emerụ ahụ na nsị-dị ka fungi nke genus Candida, dermatophytes, ebu fungi, dị iche iche pathogens nke systemic mycoses na ọbụna staphylococci na streptococci.
Kedu mgbe e nyere Ketoconazole mbadamba ọgwụ?
Ntu maka maka ketoconazole bụ:
- ọrịa na-efe efe nke tract digestive;
- ọrịa na-efe efe nke akụkụ ahụ nke urino-genitalia, gụnyere ọgwụ ndị na-egbu egbu, nke a maara nke ọma dị ka aghara, nakwa dị ka ndị nkuzi na-adịghị ala ala;
- mycosis nke mbọ, akpụkpọ, ntutu, paronychia, folliculitis;
- seborrheic dermatitis (dandruff);
- nkwụsịtụ mkpụrụedemede;
- mycosis anya;
- mycoses systemic - candidiasis, blastomycosis, histoplasmosis, wdg;
- igbochi ọrịa ndị na-efe efe na ndị na-arịa ọrịa immunodeficiency na ọnyà dị ukwuu nke ọrịa ọnya.
Mgbe a na-ekwu okwu ọnụ, ndokwa na mbadamba nkume na ketoconazole na-enye ọgwụgwọ dị irè maka nsị mycoses. A na - ejikọta ihe nke ihe a na mbibi nke usoro biosynthesis nke ergosterol phospholipids na triglycerides, bụ nke gụnyere mmepụta akpụkpọ ahụ mkpụrụ ndụ. N'ikpeazụ, mmụba na ịmepụta mkpụrụ ndụ ndị a na - adịghị emerụ ahụ na - akwụsị ma ọrịa ahụ na - alaghachi.
Mgbe a na-eji ọnụ ekwu okwu, nkwadebe na-etinye uche zuru oke, ya bụ, itinye onwe ya n'ọbara ahụ, na-ekesa ya na anụ ahụ, obere akụkụ na-abanye n'ime mmiri ụbụrụ. Mgbe absorption na tract digestive, ihe na-arụsi ọrụ ike na-ejikọta na imeju, na-ebu ọtụtụ ndị na-adịghị arụ ọrụ metabolites. A na-ewepụ ọgwụ ahụ na mmamịrị (13%), na-ewepụ ya na bile ma wepụ ya na feces (57%).
Emekarị 1-2 mbadamba na-ewere otu ụbọchị nri maka izu 2-8, dabere na oria na oke ahụ. E nwere ike inye ụmụaka ihe dịka afọ iri na abụọ.
Nkwekọrịta na mmetụta dị iche iche site na iji Ketoconazole
Keteconazole tablets from derboritis and other diseases of fungal etymology na-contraindicated na ime, na-elekọta nwa, ụmụaka n'okpuru afọ 12, ndị na hypersensitivity ka ketoconazole na oké nsogbu nke akụrụ na imeju ọrụ.
Mmetụta dị iche iche nke iwe mbadamba ihe bụ:
- nausea na vomiting;
- afọ ọsịsa;
- nsogbu ụra;
- dizziness, isi ọwụwa;
- ọnwụ ntutu;
- nkwụsị;
- ọpụpụ;
- ọchịchọ agụụ mmekọahụ na-ebelata;
- gynecomastia;
- urticaria, anụ ọkụ ọkụ;
- ntinye igwe;
- ọkụ.
Nlekọta nke mmezi nke na-adabere na ketoconazole kwesịrị ijikọta ya na nlekọta ahụike mgbe niile: nyocha ọbara, nyocha nke imeju na akụrụ ọrụ. Ekwesiri ike imegide onwe gị na nyocha onwe onye na ịṅụ onwe gị na ọgwụ ndị a. Nanị ọgwụ dọkịta na-enye ọgwụgwọ.
N'ihe banyere maningitis fungal, ojiji nke ketoconazole abụghị ihe amamihe dị na ya, ebe ọ bụ na ihe ahụ adịghị abanye n'ime BBB (ihe mgbochi hemato-encephalic).
Ntube nke dabeere na ihe a bụ hepatotoxic, n'ihi ya, a ghaghị iji usoro ahụ mee ihe mgbe uru nwere uru ga-emetụta ihe ize ndụ yiri nke ahụ. Karịsịa ọ na-emetụta ndị ọrịa ahụ na-ata ahụhụ site na oke ọrụ dị elu nke enzymes hepatic ma ọ bụ na-emebi imeju site na ịṅụ ọgwụ ndị ọzọ.
Nkwadebe na ketoconazole na mbadamba
Nke a bụ aha nke analogs nke ketoconazole na mbadamba (dịka ihe nkwụsị ọrụ):
- Mycosorrhal;
- Fungistab;
- Dermazol;
- Oronazole;
- Nizoral ;
- KetoconazoleAltapharm;
- Ketoconazole DS;
- Mikanisal;
- Livarol;
- Mikoket;
- Egwuregwu.