Alkaline phosphatase bụ protein nke na-enye usoro dịgasị iche iche nke mmeghachi omume ndị dị na ahụ. Njehie nke ihe ngosi site na iwu na-egosiputa mmepe nke ụfọdụ pathologies metụtara mmebi nke phosphous-calcium metabolism.
Ụdị nke alkaline phosphatase n'ime ọbara
Iji chọpụta ma ọdịnaya alkaline phosphatase dị ziri ezi ma ọ bụ na-agbapụta iwu, a na-eme nnyocha ọbara nke ọbara. Ekwesiri ighota na usoro nke alkaline phosphatase jikotara ya na age, nwoke ma obu nwanyi, na mgbe ufodu, onodu ogwu nke onye ahu. Ya mere, n'ime ụmụaka, ọnụ ọgụgụ a dị okpukpu atọ karịa ndị toro eto, na ụmụ nwanyị, ọkwa nke phosphatase alkaline dị ala karịa mmadụ.
Tụkwasị na nke ahụ, a ga-ahụta na akụkụ nke alkaline phosphatase ọnụ na-adabere na ndị na-emegharị ihe na-eji nyocha ọbara. Anyị na-enye ọnụ ọgụgụ dị ala.
Ụdị ọbara APF na nyocha nke ndụ (usoro oge niile):
- na ụmụaka na ndị nọ n'afọ iri na ụma - 1,2-6,3 mcd / l;
- n'ime mmadụ - 0,9-2,3 mkat / l;
- usoro nke alkaline phosphatase n'ime nwanyi bu 0,7-2,1 mc / l.
Ụkpụrụ nke mmezi na ụmụ nke enzymes e nyere na plasma ọbara:
- site na nwa rue afọ 1 - 245-255 nkeji / l;
- site na otu afọ ruo afọ 9 - 345-355 nkeji / l;
- site na 9 ruo 15 afọ - 275-285 nkeji / l;
- site na 15 ruo 18 afọ - 145-155 nkeji / liter.
Ọganihu dị ịrịba ama na mkpụrụedemede AF nke ụmụaka nọ n'okpuru afọ 9 abụghị ụdị ọgwụgwọ ma jikọta ya na mmụba nke ọkpụkpụ siri ike.
N'ime mmadụ, ọdịnaya nke enzymes nke otu a bụ ihe nkịtị:
- site na 18 ruo 45 afọ - 100-120 nkeji / liter;
- site na 45 ruo afọ 70 - 120-145 nkeji / liter;
- mgbe afọ 70 - 180-190 nkeji / liter.
Ụkpụrụ nke alkaline phosphatase n'ime plasma ọbara n'ime ụmụ nwanyị (site na nwata):
- site n'afọ 19 ruo 45 - 80-100 nkeji. / l;
- site na 45 ruo 55 afọ - 105-115 nkeji / l;
- site na 55 ruo 70 - 125-135 nkeji / l;
- mgbe afọ 70 - 155-165 nkeji / liter.
Ọ dị njọ ịgbanwe ọkwa nke enzyme n'oge ime. Nke a bụ n'ihi na e guzobere placenta n'ime ahụ nke nne n'ọdịnihu.
Ihe na-akpata ọrịa na-akpata mgbanwe na phosphatase alkaline
Tinyere nnyocha nyocha ndị ọzọ na nchọpụta akụrụngwa, nchọpụta nke ngwongwo phosphatase alkaline dị oke mkpa n'ịchọpụta ọrịa ụfọdụ. A na-ekenye ndị ọrịa nwere usoro ọgwụgwọ nke usoro endocrine, tract digestive, imeju, akụrụ. A ghaghị ọmụmụ ihe a na ndị inyom dị ime na ndị ọrịa na-akwado maka ọrụ ịwa ahụ.
N'ihi mmebi nke ngwongwo nke ngwa ma ọ bụ usoro, ọkwa nke alkaline phosphatase gbanwere. Na-enye aka na ọrịa a:
- imeju (cirrhosis, nje ịba ọcha n'anya, nje jaundice );
- bile ducts;
- ọkpụkpụ anụ (rickets, sarcoma osteogenic, osteomalacia, wdg);
- ọgwụ ọjọọ;
- ọrịa ogbu na nkwonkwo;
- nkwonkwo myocardial;
- nnukwu renal ọdịda;
- Ọrịa ulcerative colitis na ọrịa nsia na-esite na afọ ọsịsa;
- ọrịa ọgbụgba gị.
Iwu maka nyocha nke biochemical
Iji nweta data kachasị mma, ị ga-agbaso iwu ndị a:
- Ụbọchị tupu nyochaa, a machibidoro ya itinye aka na ahụ ike ma ọ bụ egwuregwu.
- Enweghị ihe dịkarịrị awa 24 na-atụ aro ka ị ghara ịṅụ ihe ọṅụṅụ na-aba n'anya ma ghara iji ọgwụ ndị na-enye aka mee mgbanwe na ọkwa nke phospkalase alkaline.
- A na-eme nnyocha ahụ na afo efu na ụtụtụ.
- A na-etinye nyocha ọbara n'ime vein maka nyocha na oke nke 5-10 ml.
Na mgbakwunye, iji dokwuo anya nyocha, mmamịrị, feces, ọgwụ intestinal nwere ike inye ya, na ịgwọ ọrịa, nsia, ọkpụkpụ, placental, isoenzymes nke alkaline phosphatase nwere ike kpebisie ike.